About N-of-One

Our company name—N-of-One—reflects our approach to personalized cancer treatment. In a typical clinical trial, the "N" stands for the number of patients enrolled. The more patients enrolled, the higher the "N", and in general large trials identify what works in the average patient. But the more we know about cancer, the less sense it makes to treat patients as if they were "average." For example, researchers estimate that there may be 20 distinct types of breast cancer alone—each one of which will respond best to a different type of therapy. Subtypes of other cancers are also emerging.

With us, each patient is not "average"; rather, each patient is the only "N". Our job begins with understanding as much as possible about each patient's cancer at the most fundamental level—it's molecular biology. Based on sophisticated genetic and molecular analyses of a patient's tumor, N-of-One brings to light information that helps patients and their physicians make truly informed decisions.

N-of-One—A Revolution in Knowledge

The explosion of cancer research has led to key advances in diagnostics and treatments. We now know that even tumors that arise in the same organ can be profoundly different at the molecular level. Figuring out the "molecular drivers" of a particular tumor may be the key to being able to slow or stop its growth. That realization has led to a new emphasis on treating cancer using specialized diagnostics to study a tumor in detail and then choosing treatments based on its molecular characteristics. This is personalized medicine.

HOW WE DO THIS: N-of-One harnesses this emerging science with a bold new model of cancer care. Our team works with a network of state-of-the-art diagnostic laboratories, leading-edge research institutions, and top cancer experts. Our team supplements, but does not replace, your own doctors. We can:

• Pinpoint the scientific advances that will change clinical practice as they occur.
• Give patients access to cutting-edge information about their disease.
• Identify diagnostic tests that provide information about the biology of an individual tumor.
  • Provide access to the highest quality and most comprehensive diagnostic tumor testing.
• Facilitate analysis of each patient's tumor and, based on this information, identify advanced treatment strategies using both standard and cutting edge therapies.

We work with each client to develop a personalized action plan based upon the individual characteristics of that patient’s cancer.

N-of-One—Independent and Unbiased

We do charge for our services. However, to serve cancer patients and their medical team with integrity, we do not profit from any laboratory testing, entry into clinical trials, or referrals to cancer centers or members of our expert network.